Fig. 6
From: Exploring the diagnostic potential: magnetic particle imaging for brain diseases
Reproduced with permission from Ref. [59] (c and d)
The potential of magnetic particle imaging (MPI) in cerebrovascular and neurodegenerative diseases. MPI was used to detect cerebral perfusion and stroke (a and b). a MPI clearly detected the ischemic area (red hash mark). b Concentration–time curves showed that MPI yields similar results to magnetic resonance imaging (MRI) but with higher temporal resolution. Reprinted with permission from Ref. [60] (a and b). The magnetoelectric effect of magnetoelectric nanoparticles (MENs) was proposed to simulate local nerve electrical activity (c and d). When coupled with MPI, it can be used to map the electric field activity of the brain in real time. c Normalized de-modulated MPI-MEN images of 2 different views of frontal lobes. d The insert shows a detailed normalized three-dimensional field profile in the region of firing.